Choroid Plexus Calcification: Causes And Detection
Choroid plexus calcification occurs when calcium phosphate or carbonate accumulate in the choroid plexus, a structure in the ventricles of the brain involved in cerebrospinal fluid production. It can be associated with infections (e.g., congenital toxoplasmosis, cytomegalovirus), hypoxia-ischemia (e.g., prematurity), congenital anomalies (e.g., trisomy 18, 21), and tumors (e.g., choroid plexus papilloma). Choroid plexus calcification can be detected on imaging tests such as computed tomography (CT) scans or magnetic resonance imaging (MRI).
Definition and brief overview of cerebral calcifications
Cerebral Calcifications: A Brainful of Crunches
Ever heard of cerebral calcifications? Picture a brain with tiny bits of calcium, like sprinkles on a donut. These calcium deposits can be a sign of various underlying issues, but don’t worry, we’re here to decode this brain candy for you!
What’s the Buzz About Cerebral Calcifications?
Cerebral calcifications are little clumps of calcium that settle in the brain tissue. They can be asymptomatic (meaning you might not even notice them) or cause a range of symptoms, depending on their size, location, and the underlying cause.
Etiologies: The Cause Behind the Crunch
The crunchy culprit of cerebral calcifications can be traced back to different factors. Let’s dive into the most common ones:
Infectious Etiologies
- Congenital Infections: If an infection sneaks into your mom’s womb during pregnancy, it can leave a calcium trail in your brain.
- Intrauterine Infections: Infections acquired after birth can also set off the calcium sprinklers in the brain.
Hypoxia-Ischemia Etiologies
- Prematurity: Babies born before their due date might have a higher chance of developing calcifications due to oxygen deprivation.
- Perinatal Asphyxia: When newborns are starved of oxygen during labor, it can lead to calcium crunchiness in the brain.
Congenital Anomaly Etiologies
- Trisomy 18: This genetic condition can cause intellectual and physical disabilities, accompanied by cerebral calcifications.
- Trisomy 21 (Down Syndrome): Another common genetic disorder that increases the risk of calcifications in the brain.
Tumor Etiologies
- Choroid Plexus Papilloma: A benign tumor in the brain’s fluid-filled cavities can trigger calcium deposits.
- Choroid Plexus Carcinoma: A more aggressive tumor in the same area can also lead to calcifications.