The “amino acid alphabet” refers to the 20 amino acids that serve as the building blocks of proteins. Each amino acid has a unique structure and chemical properties that contribute to the overall shape and function of the protein. The sequence of amino acids in a protein determines its unique properties, making it essential for…

Ionizable amino acids possess charged side chains that can exist in different ionization states depending on the pH of the surrounding environment. These charged side chains contribute to the overall charge of the amino acid, influencing its solubility and reactivity. Notably, amino acids have an isoelectric point (pI) at which they have no net charge…

If amino acids are oversupplied, they can be used for energy or converted to fat. Excess amino acids can also be converted to urea and excreted from the body. The body will use the amino acids it needs and excrete the rest. What is Protein Metabolism and Synthesis? Picture this: Your body is like a…

Nucleophilic amino acids, including serine, cysteine, and threonine, contain side chains with functional groups capable of donating electrons. Their sulfur or hydroxyl groups exhibit nucleophilic properties, enabling them to participate in reactions like alkylation, acylation, and Michael additions. These amino acids play crucial roles in enzymatic catalysis, particularly in serine proteases and cysteine proteases. They…

Amino acid therapy utilizes essential amino acids to address various health conditions. Leading medical institutions such as the NIH and Mayo Clinic recognize its significance. Prestigious academic institutions like Harvard and UCLA advance the field through research and education. Specialized organizations like the American College of Nutrition and the NIH’s Office of Dietary Supplements provide…

Amino acids and electrolytes are essential for maintaining bodily functions. Amino acids, the building blocks of proteins, provide energy and aid in tissue repair. Essential electrolytes, including sodium, potassium, calcium, and magnesium, regulate fluid balance, nerve impulses, and muscle contractions. Electrolyte imbalances can occur due to dehydration, overhydration, or acid-base imbalance. Replacement therapy via intravenous…

Amino acid oxidation is a crucial metabolic process in which amino acids, the building blocks of proteins, are broken down to generate energy or intermediate molecules for other biochemical pathways. This complex process involves multiple enzymes that catalyze specific reactions, leading to the formation of ammonia, carbon dioxide, and intermediates like pyruvate and acetyl-CoA. Amino…

Mass spectrometry (MS) measures the mass-to-charge ratio (m/z) of molecules to determine their elemental composition and structure. In amino acid analysis, MS can identify and quantify individual amino acids based on their unique m/z values, aiding in protein characterization and sequencing. Unveiling the Amino Acid Secrets: A Mass Spectrometry Adventure Picture this: you’re a tiny…

Amino acids, the building blocks of proteins, are organic molecules characterized by an amino group, a carboxylic acid group, and a side chain that determines their chemical properties. These monomers link together via peptide bonds to form peptides, small chains of amino acids, and further into complex protein structures. Proteins exhibit diverse functions, including catalysis…

Rice is a staple grain that provides a range of essential and non-essential amino acids. Essential amino acids, such as leucine and lysine, are vital for protein synthesis and cannot be produced by the body. Rice also contains non-essential amino acids like alanine and glycine, which play supporting roles in protein synthesis. Rice proteins, including…

Counting Amino Acids: Amino acids are the building blocks of proteins, and determining their quantity is crucial in understanding protein structure and function. Quantitative amino acid analysis involves a range of methods, including chromatography, electrophoresis, and spectrophotometry. These techniques allow researchers to accurately measure the concentration of various amino acids within a protein sample, providing…

Calcitonin, a crucial hormone in calcium metabolism, is closely related to calcitonin gene-related peptide (CGRP), involved in pain and vasodilation, and medullary thyroid carcinoma, where calcitonin levels are elevated. Its moderate closeness to carboxypeptidase A and hypocalcemia highlights its role in calcium regulation and the consequences of low calcium levels. Calcitonin influences calcium channels, signaling,…